Undiagnosed Celiac Disease and Fertility

Disclaimer: this information is not meant to treat, cure or diagnosis any condition. It is purely educational and informative information.


According to several medical journals, undiagnosed Celiac Disease can cause a wide range of gynecological and obstetric issues including delayed menus, early menopause and secondary amenorrhoea.

Women with undiagnosed celiac disease have been shown to have up to a nine-fold relative risk of recurrent miscarriage compared with treated patients.(treatment referring to adherence to a gluten-free diet)

Nutritional Deficiencies due to malabsorption can cause reproductive and pregnancy complications. Undiagnosed celiac disease may cause folic acid, vitamin B12, fat-soluble vitamin and iron deficiencies, which may further adversely effect Fertility.

Gliadin may also induce an inflammatory reaction with associated cytokine production, which may adversely affect the fetus. Adherence to a gluten-free diet has been shown to reduce circulating autoantibodies and the risk of possible miscarriage.




This information highlights the need for early diagnosis for Celiac Disease (not to ignore symptoms, thinking it is just a gluten sensitivity) because the consequences of staying undiagonosed and thus failing to adhere to a strict life-long gluten avoidance can possibly lead to problems such as discussed here.

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